Calcium salts in living organisms play an important
regulatory and structural role. Calcium (Ca2+) is a common macronutrient in the
body of plants, animals and humans. This chemical element is involved in key
physiological and biochemical processes of the cell. Calcium ions are involved
in blood coagulation processes, and also serve as one of the universal second
messengers inside cells and regulate a variety of intracellular processes -
muscle contraction, exocytosis, including the secretion of hormones and
neurotransmitters. In the body, calcium is found not only in bones and teeth
(about 1 kilogram), but also in the blood (about 0, kilogram). Calcium in the
bones is mainly needed for our skeleton to be strong and able to support us.
Calcium helps muscles contract, nerves carry messages from the brain to every
part of the body, blood vessels move blood throughout the body, release
hormones and enzymes that affect almost every function in the body, blood clot,
regulate blood pressure and bad cholesterol levels. The main disease caused by
calcium deficiency is osteoporosis. This is a disease in which the structure
and strength of the bone is disturbed and the risk of fractures increases. Why
is too much calcium dangerous? A long-term increase in the level of calcium in
the blood (hypercalcemia) is not felt in any way, but significantly increases
the risk of kidney stones, gallstones and bladders, stomach ulcers,
hypertension, vasoconstriction, and heart disease. In old age there is an
accumulation in the body of minerals, especially calcium. This is expressed in
the deposition of calcium salts in the walls of blood vessels, in joints,
cartilage and other tissues. The amount of deposited calcium salts on the
tissues of the body is very large, if not huge. Along with this, cases of
senile osteoporosis associated with salt deficiency are known [1-3]. Thus, in
old age, in some cases, there are phenomena of oversaturation with salts, and
in other cases, insufficiency of calcium salts. Once again, it is important to pay
attention to the fact that oversaturation of body tissues with calcium salts is
associated in patients with hypercalcemia. It appears that older people who are
prescribed calcium supplements for the prevention of osteoporosis suffer from
an increase in the content of calcium in the tissues much more than from
osteoporosis. And, indeed, in recent years, in developed countries, calcium
preparations are widely prescribed for the prevention of age-related bone
fragility for the elderly. But evidence of their safety has been obtained in
animal studies. And recently it turned out that calcium can contribute to a
more severe course of cardiovascular diseases [4]. So, we are dealing with a
dilemma - in the course of their life, older people accumulate a very large
amount of calcium salts, which, settling on various organs, in some cases
inhibit their functioning, and in other cases lead to early degeneration of
many organs and organ systems, leading to the emergence of degenerative
diseases - Parkinson's disease, Alzheimer's disease, multiple sclerosis and
many other diseases.This is not about an increase in the calcium content in the
blood - hypercalcemia, but about an excess amount of calcium salts deposited on
tissues - the spine, joints, nerve structures of the brain and other structures
(calcification). What should be the doctor's position - to give preference to
the creation of methods for the treatment of excess amounts of calcium salts in
the body or methods for the treatment of osteoporosis? It seems to us that the
extremely important task of the present time is to cure those conditions,
especially in the elderly, which lead to the elimination of excess amounts of
calcium salts in the tissues (calcification), which leads to the occurrence of
a large number of degenerative diseases. This article is dedicated to just
that. The deposition (deposition) of calcium salts in various tissues, as well
as in various bone formations - calcification or calcification - is a
degenerative-dystrophic disease. In the spine, with calcification - damage to
the ligaments, areas appear in the thickness of the fibers where the connective
tissue is replaced by salt formations. Calcification can also occur in various
brain structures, namely, in those structures that are affected in Farah's
disease, for example, in those brain structures that become pathological in
Alzheimer's disease. Fahr's disease is an idiopathic non-atherosclerotic
symmetric intracerebral calcification of the cerebral cortex, basal ganglia and
cerebellar dentate nuclei associated with the deposition of calcium salts in
the walls of small arteries and arterioles, as well as in the substance of the
brain, namely in those structures that are affected in Alzheimer's disease.
Morphologically, calcifications are found symmetrically in various structures:
the cerebral cortex, white matter, subcortical ganglia, internal capsule,
cerebellum, walls of small arteries, less often veins [5,6]. If calcification
of brain structures occurs in Farah's disease, it is possible that a similar
phenomenon may also occur in Alzheimer's disease. The deposition of calcium
salts in the back - calcification and the deposition of uric acid - gout. They
are deposited in the form of crystals of urate salts in the area of large and
small joints. When calcium is not absorbed by bone tissue, it begins to be
deposited in various other tissues of the body. This is a systemic reaction.
What does "systemic response" mean? In a systemic reaction, calcium
salts are deposited not only in the spine, but also in other organs and
tissues, including in the structures of the brain associated with the
occurrence of Alzheimer's disease -: amygdala, basal nucleus, insular cortex,
brain septum, hippocampus, neocortex , temporal lobe, parietal lobe, isocortex,
piriform lobe, insular field, hippocampal pre-basement, paralimbic cortex. The
salts deposited on the tissues change the structure of the tissue. This leads
to disruption of microcirculation of blood and lymphatic fluid, which leads to
degeneration of brain structures. Treatment of salt deposits in the spine at
all stages lends itself to manual methods of influence, massage in combination
with therapeutic exercises and kinesiotherapy, allows you to remove salts and
restore the physiological structure of tissues affected in the spine. Treatment
of calcifications, calcifications of the spine and joints is preceded by the
need to exclude vitamin D deficiency in the blood, high levels of uric acid.
All of the above is associated with the treatment of calcification, calcification
of the spine and joints. Does everything said apply to calcification,
calcification of the nervous structures of the brain, emerging calcific
degeneration? For example, to those structures with which the occurrence of
Alzheimer's disease is associated? If calcification of brain structures occurs,
there is no possibility to perform manual therapy or massage of brain
structures. That is why a different therapeutic approach is needed for the
treatment of calcification of the nervous structures of the brain. This article
is devoted specifically to the treatment of calcification (but not calcium) of
brain structures in Alzheimer's disease in the elderly. In AD, the formation of
neurofibrillary glomeruli in the nervous structures, the accumulation of beta-amyloids
and tau proteins occur. Pathological forms of beta-amyloids are formed in all
people, but they are eliminated from the brain and do not cause problems.
Patients with AD have a violation of the elimination of pathological
beta-amyloids and tau proteins. It is well known that in old age there is a
violation of the elimination of pathological formations due to calcification of
the kidneys. It is possible that the normalization of the calcium content in
the kidneys can normalize this problem [7,8].